Michele Brambilla was born in Monza in 1958. He graduated in History from the Faculty of Letters and Philosophy of the University of Milan, and became a professional journalist in 1984. He started in 1976 on the local biweekly Il Cittadino, while in 1978 he was a correspondent from Brianza and the province of Milan for Il Giornale. He worked at the Corriere della Sera in Milan from 1985 to 2002: at the Corriere he was a reporter, then deputy chief reporter of Milan, then deputy editor-in-chief of Culture and of the Sette magazine.
On 12 October 2002 he became director of the newspaper La Provincia. From May to the end of November 2006 he was deputy director of Libero. From 1 December 2006 to August 2009 he was deputy director of the newspaper Il Giornale. Since September 2009 he has been at La Stampa, first as a correspondent-columnist and since September 2014 as deputy director. From 23 November 2015[2] to 28 February 2019 he was director of the Gazzetta di Parma.
In March 2019 he took over the direction of QN Quotidiano Nazionale (a consortium that brings together the four newspapers La Nazione, Il Giorno, Il Resto del Carlino and Il Telegrafo) succeeding Paolo Giacomin.
Catholic, he wrote several texts dedicated to faith. A critic of the years of protest, he dedicated a long essay to it, Ten Years of Illusions. History of ’68, closed in a sharp way: “In short, it seems that every hope of ’68 has turned into its opposite.” The period of terrorism and the bias of many names in Italian journalism are the topic of his previous book L’Eskimo in editoriali, reprinted several times over the years.